It is claimed time after time by the media, in the past few days that the Orlando shooting was the ‘deadliest’ mass shooting in history.
This is incorrect and very misleading. “Wounded Knee” is, where the U.S. Government massacred over 250 Sioux men, women and children. The Native Indians, were massacred.
Yes, one of the largest mass shooting in the U.S.’s history happened in America, in 1890.
When 300 Sioux Indians, Native Indians, at Wounded Knee Creek in South Dakota were murdered by federal agents and members of the Cavalry who came to take away the firearms who were rightfully owned by them. Their excuse was that they needed to take away the firearms “for their own safety and protection.”
After the Native Indians handed their firearms over, the cavalry began shooting at every Sioux member, men, women and children were slaughtered.
Out of the 300 victims, 200 of whom were women and children.
Dr. Mooney makes mention that there is no doubt that this was a massacre, they were shooting fleeing Indian women with infants in their hands. 
Dr. James Mooney on the massacre:
“At the first volley the Hotchkiss guns trained on the camp opened fire and sent a storm of shells and bullets among the women and children, who had gathered in front of the tipis to watch the unusual spectacle of military display. The guns poured in 2-pound explosive shells at the rate of nearly fifty per minute, mowing down everything alive. The terrible effect may be judged from the fact that one woman survivor, Blue Whirlwind, with whom the author conversed, received fourteen wounds, while each of her two little boys was also wounded by her side. In a few minutes 200, Indian, men, women and children … were lying dead and wounded on the ground, the tipis had been torn down by the shells and some of them were burning above the helpless wounded, and the surviving handful of Indians were flying in wild panic to the shelter of the ravine, pursued by hundreds of maddened soldiers and followed up by a raking fire from the Hotchkiss guns, which had been moved into position to sweep the ravine. there can be no question that the pursuit was simply a massacre, where fleeing women, with infants in their arms, were shot down…” (Documenting American Violence: A Sourcebook [Oxford University Press, 2006] by James Mooney, page 240)
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 “More than 4,000 black men, women, and children died at the hands of white mobs between 1877 and 1950. This new memorial in Alabama shows what black communities in the South saw over and over again – black bodies, mutilated and raised up, as a clear threat.” (“This new lynching memorial rewrites American history” (9th April 2018), https://edition.cnn.com/travel/article/lynching-memorial-montgomery-alabama/